Tag Archives: Antimicrobial Resistance

Do Cattle Bacteria Contribute to Antibiotic Resistance in Human Medicine?

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This article written by Dr. Reynold Bergen, BCRC Science Director, originally appeared in the November 2020 issue of Canadian Cattlemen magazine and is reprinted on the BCRC Blog with permission of the publisher.

E. coli live in the digestive tracts of warm-blooded animals and birds. Most are harmless, some are beneficial, and some (like E. coli O157:H7) can be very dangerous. E. coli are also involved in antibiotic resistance.

“Extended-spectrum beta-lactamase producing” (or ESBL) E. coli are a major concern in human medicine. These bacteria are resistant to many antibiotics used in both human and veterinary medicine. Ordinary E. coli can cause urinary tract or bloodstream infections in people. They’re usually quite easy to treat with antibiotics. But if ESBL E. coli are responsible, the infection can’t be easily treated with antibiotics, and the illness can be much worse or even fatal.

E. coli rarely causes disease in feedlot cattle. But ESBL E. coli are still a concern, because antibiotic resistance genes are often located on “mobile genetic elements” that bacteria can trade with each other, even with completely unrelated bacteria. So antibiotic resistant BRD bacteria like Mannheimia, Pasteurella or Histophilus can spread their antibiotic resistance genes to each other, or possibly to E. coli. That’s like a border collie developing horns after a day of herding Herefords. Continue reading →

On-Farm Antimicrobial Surveillance Moves a Step Closer

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This article written by Dr. Reynold Bergen, BCRC Science Director, originally appeared in the September 2019 issue of Canadian Cattlemen magazine and is reprinted on the BCRC Blog with permission of the publisher.

As long as cattle continue to get sick, cattle producers will need antimicrobials to help them recover. At the same time, it’s common to hear activists, regulators, consumers and/or retailers call for livestock producers to stop using antimicrobials altogether, reduce antimicrobial use, or demonstrate that antimicrobials are being used responsibly. Solid, reliable data demonstrating our industry’s antimicrobial use (AMU) practices and antimicrobial resistance (AMR) prevalence on an ongoing basis are key to maintaining consumer and public confidence in Canadian beef production practices.

The Public Health Agency of Canada monitors antimicrobial resistance in healthy beef cattle, pigs and poultry arriving at abattoirs as well as retail meat through the Canadian Integrated Program for Antimicrobial Resistance Surveillance (CIPARS). CIPARS has also had on-farm programs to collect antimicrobial use (AMU) and resistance (AMR) data for poultry and grower-finisher swine for several years. Continue reading →

Does Antibiotic Resistance Move Through the Environment?

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This article written by Dr. Reynold Bergen, BCRC Science Director, originally appeared in the December 2018 issue of Canadian Cattlemen magazine and is reprinted on the BCRC Blog with permission of the publisher.


Recent columns have talked about antibiotic use in Canadian cow-calf and feedlot operations. Contrary to common misconceptions, antibiotic resistant bacteria are very unlikely to transfer from cattle to beef, evade food safety interventions in the processing plant, survive cooking, and cause an antibiotic resistant infection in a person. But can antibiotic resistant bacteria be transmitted from cattle, through feedlot manure and runoff, across soil, through wetlands, streams and rivers, and reach humans through the environment?

A Beef Science Cluster study led by Dr. Rahat Zaheer and Tim McAllister of Agriculture and Agri-Food Canada (with collaborators from the Public Health Agency of Canada, the University of Calgary’s faculties of medicine and veterinary medicine, University of Guelph, Alberta Agriculture and Feedlot Health Management Services) examined this question.

What they did: This research focused on bacteria called enterococci that can cause infections in humans (e.g. urinary tract, liver and bile duct, heart, surgery wound, and bloodstream infections). Most enterococcal infections can be effectively treated with macrolide antibiotics. This is important because macrolides (products like Draxxin, Zuprevo, Micotil, Tylan, Zactran, etc.) are commonly used in both beef production and human medicine.

Over a two-year period, this team collected samples from feedlots (pen floor fecal samples, collection ponds, stockpiled and composted manure), agricultural soils, wetlands, streams, municipal sewage, packing plants, retail meats and human patients. Advanced lab testing was used to identify the specific types of enterococci and antibiotic resistance patterns in the samples from each location.

Continue reading →

Q&A on conventional production of Canadian Beef

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Do growth promoting, antimicrobial or other veterinary drugs affect the food safety of Canadian beef?



Veterinary drugs are regulated by the Food and Drugs Act and Regulations. All veterinary drugs go through a Health Canada approval process before they are licensed for use.  The Health Canada Veterinary Drug Directorate (VDD) evaluates and monitors the safety, quality and effectiveness, and sets standards for the use of veterinary drugs to ensure that, when used according to label directions, they are safe for both animals and humans.

For a more detailed explanation of the veterinary drug approval process in Canada, download ‘Canada’s Veterinary Drug Approval Process‘

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Label and veterinary directions indicate proper administration doses and routes for veterinary products, as well as pre-slaughter withdrawal times, which ensure that the product has been metabolized by the animal before the meat is harvested. Most drugs are completely metabolized during the prescribed minimum number of days between the last administration of the drug and slaughter, and therefore leave no residue. Continue reading →

This December you’ll need a prescription to buy virtually any livestock antibiotic

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Editors note: This post was originally published February 1, 2018. A French version of the 2-page handout has been added and minor revisions to the article below have been made to reflect current information.

If you haven’t done so already, develop a relationship with a beef veterinarian.



Starting December 1, 2018, Health Canada is introducing a couple of important changes affecting the way animal antibiotic products can be accessed by producers across Canada. And having an established Veterinary-Client-Patient Relationship (VCPR) will be an important part of a smooth transition. (see sidebar below)


Click image to download a two page handout on the changes to how antibiotics can be purchased. Handout includes a list of cattle products that will need a prescription as of December 1, 2018. (version française)

The key point is, starting Dec. 1, 2018, all livestock producers in Canada will need a prescription from a licenced veterinarian, before they can buy a medically important antibiotic (MIA) for therapeutic use in livestock production. This applies to all beef cattle sectors using antibiotics — cow-calf operators, feedlots and feedmills (and really all sectors of animal agriculture including beef, dairy, hogs, sheep, horses, fish and even bees). The new policy doesn’t just apply to injectable products, but also includes some boluses and calf scour treatments, and Component and Compudose implants. At the same time, the new policy does not apply to certain antimicrobials such as the ionophores, which are not considered to be medically important in managing disease in humans. Continue reading →

This December, you’ll need a prescription to buy virtually any livestock antibiotic

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Note: Updated version published here September 10, 2018.

If you haven’t done so already, the first few months of 2018 would be an excellent time to develop a relationship with a beef veterinarian.



Starting late in 2018, Health Canada is introducing a couple of important changes affecting the way animal antibiotic products can be accessed by producers. And having an established Veterinary-Client-Patient Relationship (VCPR) will be an important part of a smooth transition. (see sidebar below)


Click to download a two page handout on the changes to how antibiotics can be purchased. Handout includes a list of cattle products that will need a prescription as of December 1, 2018.

The key point is, starting Dec. 1, 2018, all livestock producers will need a prescription from a licenced veterinarian, before they can buy a medically important antibiotic (MIA) for therapeutic use in livestock production. This applies to all beef cattle sectors using antibiotics — cow-calf operators, feedlots and feedmills Continue reading →

Antibiotic Alternatives

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This article written by Dr. Reynold Bergen, BCRC Science Director, originally appeared in the October 2016 issue of Canadian Cattlemen magazine and is reprinted on the BCRC Blog with permission of the publisher.


AntibioticCCM
Antibiotics are a tremendously valuable tool in livestock production. For example, at this time of year, groups of light-weight, freshly weaned, shrunk-out calves with an unknown vaccination or nutritional history arriving at a feedlot after being transported long distances from pre-sort sales in cool, wet fall weather are likely candidates for bovine respiratory disease (BRD). Treating these calves with a preventative antibiotic (metaphylaxis) after they arrive at the feedlot can greatly reduce health problems, suffering and death losses in these calves during their first few weeks on feed.

Bacteria will develop resistance to antibiotics that are used routinely on the ranch or in the feedlot, so these antibiotics will become less effective for preventing or treating disease. This doesn’t directly translate to a concern about antibiotic resistant bacteria in retail beef.
In fact, antibiotic resistance surveillance has Continue reading →

Bov-Innovation: Putting Theory into Practice

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This article written by Dr. Reynold Bergen, BCRC Science Director, originally appeared in the June 2016 issue of Canadian Cattlemen magazine and is reprinted on the BCRC Blog with permission of the publisher.


bovinnovation
There is no shortage of beef industry conferences, workshops and meetings for Canadian beef producers to attend throughout the year. These have included the Canfax forum, the Canada Beef forum, Cattlemen’s Young Leaders forums, industry golf tournaments, tours, national, provincial and breed association meetings, the International Livestock Congress, and many more. Although they are valuable events, it is hard for producers to attend every event they might wish to. It can also be frustrating when similar speakers or themes get addressed at several different meetings, and busy producers take extra time away from their operations to hear the same presentations multiple times. The last thing anyone needs is to make time for yet another industry event.

Continue reading →

National Beef Antimicrobial Research Strategy developed to drive solutions

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News Release
May 9, 2016

Calgary, AB – As concerns grow about the continued effectiveness of antimicrobials in human health and questions arise about the contribution of modern beef production to antimicrobial resistance in human medicine, the beef industry is increasingly pressured to reconsider its methods of combatting harmful bacteria in cattle. Research will play a critical role in the industry’s ability to reduce medically-important antimicrobial use and to develop, identify and implement effective, responsible alternatives to antimicrobials.

“There’s no doubt antimicrobial resistance, use and their alternatives are a high priority in terms of policy, research, and regulations,” said Tim Oleksyn, a cow-calf producer from Shellbrook, Saskatchewan and Chair of the Beef Cattle Research Council (BCRC).  “It is important for the industry to have a comprehensive strategy with clearly defined outcomes to ensure every research dollar helps make progress in addressing human health and public confidence concerns, while also ensuring animal welfare and industry sustainability are maintained.”

Due to the importance and priority placed on antimicrobial resistance and use, funding of Continue reading →

Antimicrobial use and resistance in beef cattle: what producers need to know; Webinar March 2

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Update: Missed the webinar? Find the recording and check for future webinars on our Webinars page: http://www.beefresearch.ca/resources/webinars.cfm

In Canada, surveillance indicates that antimicrobial resistance levels in cattle and beef are extremely low and have not increased over time.

Join this free webinar to learn more about why resistance is low, and what precautions beef producer can take to continue this trend.

When


Wednesday March 2 at 7pm MST

  • 6:00pm in BC
  • 7:00pm in AB
  • 8:00pm in SK and MB
  • 9:00pm in ON and QC
  • 10:00pm in NS, NB and PEI 

Watching on a tablet or mobile device?

If you plan to join the webinar using Continue reading →